Pitt Hopkins is a rare and severe neuro-developmental disorder caused by a mutation of the TCF4 gene on the 18th chromosome. It is characterized by profound developmental delays, problems with motor coordination (ataxia) and balance, breathing abnormalities, intellectual disability and possible seizures. Most individuals with Pitt Hopkins do not develop functional speech. Pitt Hopkins affects all races and both genders equally.

Since the gene that causes Pitt Hopkins was only found in 2007, currently there are less than 300 children in the world diagnosed with this syndrome, however we believe there are many more. Because loss of TCF4 prevents neurons from functioning properly, our scientist believe that studying Pitt Hopkins will also give us important insight into other neurological disorders like Alzheimers, Autism and Epilepsy.

For more information on Pitt Hopkins please visit www.pitthopkins.org

The mission of the Pitt Hopkins Research Foundation (PHRF) is to support research dedicated to finding a treatment, and hopefully an eventual cure of Pitt Hopkins and other similar disorders. Made up of families for families, the PHRF is also dedicated to supporting children with Pitt Hopkins with resource recommendations, parental support and the latest medical information. With cutting edge research, we HOPE for a brighter future for our children and children with similar disorders.

For this ride, every dollar raised for Pitt Hopkins (up to $50,000) will be doubled and 100% of the donation will go to research.