Susan K. Axler Foundation 2-PREVENT Translational Center of Excellence Fund
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  Our Guest Speaker: Dr. Angela DeMichele  
Recent donations (16 donations)
Name DescendingX Amount
Dr. Douglas Finkel $100.00
Robyn Latman $20.00
Roz Stern $100.00
Carol Greco
Women's Connection $1500.00
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Susan K. Axler Foundation for Breast Cancer Cures, Inc.


Susan Axler was a tireless advocate for research and advances in therapies leading to the cure of breast cancer. Sue battled metastatic breast cancer for 17 years during which time she volunteered, participated in major cancer grant review panels, attended conferences, and inspired many others to volunteer.

The Susan K. Axler Foundation, a 501(c)(3) established by her family within a year of her death in 2017, is primarily directing its efforts to Penn Medicine's 2-Prevent Translational Center of Excellence (TCE) at the Abramson Cancer Center of the University of Pennsylvania.

The mission of TCE is to work together as a multi-disciplinary team of Penn scientists and breast cancer clinicians to understand why some women have recurrence. This is accomplished through prediction, prevention, monitoring, detection, and treatment measures. The TCE aims to address one of the major challenges in breast cancer treatment: The high rate of relapse and late treatment effects among breast cancer survivors.

Approximately 30 percent of breast cancer patients ultimately relapse, and many more experience late effects of treatment or are diagnosed with a second cancer. Breast cancer research and treatment have long focused on a patient's original tumor as a guide to preventing relapse; however, research suggests that some recurrent cancers are different from the primary tumor and may respond better to different therapies. This has led millions of breast cancer survivors without meaningful measures to monitor and prevent recurrence in a more proactive way.

The TCE's clinical trials underway are aimed at stopping the return of breast cancer for women who have in the past undergone treatment for primary breast cancer. For women with higher risk of recurrence, successful trial outcomes will lead to important cure outcomes.

The TCE is led by Lewis Chodosh, MD, PhD and Angela De Michele, MD, MSCE. The Abramson Cancer Center had more nationally recognized research and recurrent breast cancer in the basic sciences labs and in the clinic - than any other cancer center in the country. This makes Penn well positioned to address the challenges of breast cancer, recurrence and metastatic disease.
Danny Axler-Super Ball Tribute February 2025****** Clincal Trials Webinar Update by Dr. Angela DeMichele, December 3rd, 2024
Sue passed away over seven years ago, but her strong dedication to a cure for breast cancer continues. She would be grateful to learn that the clinical trials are showing very promising results towards the goal to prevent metastatic breast cancer and especially proud of her grandson Danny's tribute fundraiser that raised more than $2,000.

In another recent tribute close to 80 Women's Connection (WC) members and guests from 16 different states registered for the WC sponsored Webinar by Dr. DeMichele. Her presentationt provided valuable educationl information and raised more than $4,000. One UPenn trial demonstrated that it's possible to find and treat these dormant cells, showing promise for preventing relapse. For additional information see 2-PREVENT Breast Cancer TCE

If interested in participating in these clinical trials we encourage you to email the program administrator at BreastCancerClinicalTrials@pennmedicine.upenn.edu

DONATIONS: There are no administrative fees for donations. (see Donate Now link on this page)

If donating by check please make the check payable to Trustees of the University of Pennsylvania. In the check memo note Susan K. Axler Foundation. Mail to: Penn Medicine Development Office Attn: Madeleine Hansen 3535 Market Street Suite 750 Philadelphia, Pa 19104.
    Donation messages
    I hope a cure is close! --Dr. Douglas Finkel
    We are happy to contribute to this important research. --Shira Kramer and Leon Josowitz
    To remember Sue and to honor Mike who carries the cause so close to his heart. --Ray and Sally
    We are honored to contribute to this important and life saving cause and are eager to see more effective and less debilitating cures developed in the near future. Ruth and Jack --Ruth and Jack Laks
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