Million Dollar Bike Ride-CADASIL Fund
Donate now!
   
Fundraising goal $20,000.00
Recent donations (54 donations)
Name DescendingX Amount
Christi and Devin Lushbaugh $3000.00
Anonymous $50.00
Mike Eichten Family $50.00
Neil $50.00
Rick S
Next
Recent donations
Team CADASIL 2019 Million Dollar Bike Ride

Team CADASIL is participating in the Million Dollar Bike Ride for the first time!
cureCADASIL has partnered with Penn Medicine Orphan Disease Center to participate in the Million Dollar Bike Ride! In four years, the Million Dollar Bike Ride's 25+ teams have raised over $6.4 million to fund research grants on the rare diseases they represent. The Orphan Disease Center ensures that 100% of the funds raised goes towards these pilot grants, with no overhead taken out.

All donations to Team CADASIL will be matched, up to $30,000, by UPenn Orphan Disease Center to fund a new research grant for CADASIL. This opportunity could bring an astonishing $60,000 for CADASIL specific research grant with your help.

Our timeline is short to reach our overall goal of raising a minimum of $20,000 by June. Support Team CADASIL and share this link with friends and family and through social media. Donate $5, $10, $25 - every gift matters!
Our Team needs you too!
****OUR AMAZING TEAM CADASIL RIDERS****

Conquer CADASIL - Kennedy Family -http://givingpages.upenn.edu/conquercadasilkennedy
Dorothee Rides for CADASIL- http://givingpages.upenn.edu/DorotheeRidesforCADASIL
Michelle rides for Steve - http://givingpages.upenn.edu/ForSteve
Cayla and Sandy Ride for CADASIL - http://givingpages.upenn.edu/cureCadasil

****Team CADASIL MDBR Support Pages*****

In Memory of R. Sean White - http://givingpages.upenn.edu/RememberingSean
Local NJ Awareness Walk supporting MDBR - http://givingpages.upenn.edu/KeyasteeIshmeal
In honor of Freddie: http://givingpages.upenn.edu/Freddie
NC CADASIL Awareness 5K - http://givingpages.upenn.edu/NCRunWalk
The Carney Family - http://givingpages.upenn.edu/TheCarneys

If you are unable to be a rider, you can still participate! Create a Penn Giving Page that will support Team CADASIL and the fund at UPenn for CADASIL research.
For directions on how to create a personalized Giving Page, please visit: http://www.milliondollarbikeride.org/faq/
Choose "Fundraising", then "How to create a Penn Giving page", then choose CADASIL. Questions? info@cureCADASIL.org
What is CADASIL?
CADASIL is a rare, autosomal dominant genetic disorder caused by a mutation of the NOTCH3 gene on the 19th chromosome. Hallmark symptoms of CADASIL may include: recurrent strokes, cognitive impairment, migraine with aura, and psychiatric disturbances. These symptoms are caused by damage to small blood vessels, especially those within the brain. The specific symptoms and severity of the disorder can vary greatly among affected individuals, even among members of the same family. Despite this variability, most individuals (approximately three out of four patients) experience recurrent stroke or transient ischemic attacks (TIAs), beginning at 40-50 years of age. CADASIL affects all races and both genders equally, each child of a parent with CADASIL has a 50% chance of having the disorder.

CADASIL is an acronym that stands for:
(C)erebral - relating to the brain
(A)utosomal (D)ominant - a form of inheritance in which one copy of an abnormal gene is necessary for the development of a disorder
(A)rteriopathy - disease of the arteries (blood vessels that carry blood away from the heart)
(S)ubcortical - relating to specific areas of the brain supplied by deep small blood vessels
(I)nfarcts - tissue loss in the brain caused by lack of blood flow to the brain, which occurs when circulation through the small arteries is severely reduced or interrupted
(L)eukoencephalopathy - lesions in the brain white matter caused by the disease and observed on MRI.

The diagnostic test for CADASIL was discovered in the early 2000s. Many individuals have been misdiagnosed with Multiple Sclerosis and other neurologic disorders.
Why We Need You!
The Penn Medicine Center for Orphan Disease Research hosts this event to raise money for research in rare diseases such as CADASIL, and they will MATCH EVERY DOLLAR DONATED!! (up to $30,000) Please consider donating to our cause and being a part of transformative research. 100% of your donation will go towards a new CADASIL research grant through UPenn!
  • Dominant rare disease impacting multiple generations of those diagnosed
  • Partnership with cureCADASIL Non-profit Organization
  • Support someone with CADASIL that you love
  • Rare diseases impact more people than cancer
  • 100% of your donation is tax-deductible
  • Give some amazing families hope
  • Support of one person can and does make a difference
Donation messages
In honor of Harmon Lushbaugh --Christi and Devin Lushbaugh
Go Cayla Go!!! --Neil
In Memory and Honor of Steve McGuinness --Ed & Sharon Chapman
In honor of Laura Howe and Nancy Mauer's friendship. --Nancy and David Hurt
In memory of my beautiful wife Edwina Arndt and hope for my son Randy Arndt --Mr. Harold Arndt
An effective cure for this devastating genetic disease is clearly within reach. With funding and focus, we'll get there. --Richard Fenton and Hollyday Hammond
Thank you, thank you, thank you for helping to find a cure. --Bagneschi Family
Next
Donate!

Share this page with your friends
Post fundraising progress

delrossi@upenn.edu | Anne Marie Del Rossi, Director, Data Services | 215.898.3062
2929 Walnut Street, Suite 300 Philadelphia, PA 19104 | Superuser