Over the last 4 years, Team SRS! has raised over $350,000 and funded eight research grants that were awarded to top scientists at leading institutions! Thank you for making this possible!

1) Dimethylspermine (Me2Spm) as a novel treatment approach to restore normal spermidine/spermine ratios in Snyder-Robinson Syndrome (SRS) models - Robert Casero, PhD; John Hopkins University School of Medicine

2) Self-immolating NanoSpermine as a novel treatment approach to restore normal spermine/spermidine ratios in SRS models - Robert Casero, PhD; John Hopkins University School of Medicine

3) Skeletal stem cells to treat the bone defects of patients with SRS -
Fernando Fierro, PhD; University of California, Davis

4) Modelling osteogenesis of SRS patients by targeting Spermine Synthase using CRISPR/Cas9 in human bone marrow derived mesenchymal stem cells - Fernando Fierro, PhD; University of California, Davis

5) Mechanisms of mitochondrial toxicity in SRS - Grace Zhai, PhD; University of Miami Miller School of Medicine

6) Role of mitochondria and ROS in etiology of SRS - Charles Schwartz, PhD; Greenwood Genetic Center

7) Expanding the Breadth of Metabolite Analysis for SRS - Tim Wood, PhD; Greenwood Genetic Center

The progress we've made, and the hope it represents, would NOT have been possible without support from donors like you and the generosity of Penn Medicine!